Cushing's Clinical Trials

From NIH (7/8/2008)

1		Recruiting		Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion
				Condition:		Cushing's Syndrome
				Intervention:		Drug: Mifepristone
2		Recruiting		Diagnostic Performance of Screening Tests for Cushing's Syndrome
				Condition:		Cushing's Syndrome
				Intervention:
3		Recruiting		A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome
				Condition:		Cushing's Syndrome
				Intervention:		Drug: mifepristone
4		Active, not recruiting		Study of Hypercortisolism in Cushing's Syndrome and Stress-Induced Pseudo-Cushing's Syndrome
				Condition:		Cushing's Syndrome
				Intervention:
5		Active, not recruiting		Jugular Vein Sampling for Hormone Levels for the Diagnosis of Cushing Syndrome
				Condition:		Cushing's Syndrome
				Intervention:
6		Completed		Long Term Post Operative Follow-Up of Cushing Syndrome
				Condition:		Cushing Syndrome
				Intervention:
7		Recruiting		New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome
				Condition:		Cushing Syndrome
				Intervention:
8		Active, not recruiting		Extension Study to Assess the Safety and Efficacy of Pasireotide in Patients With Cushing's Disease
				Condition:		Cushing Disease
				Intervention:		Drug: Pasireotide
9		Completed		Study of Cushing's Syndrome Not Related to ACTH Production
				Conditions:		Cushing's Syndrome; Healthy
				Intervention:
10		Recruiting		Insulin Sensitivity and Substrate Metabolism in Patients With Cushing's Syndrome
				Conditions:		Cushing's Syndrome; Insulin Resistance
				Intervention:		Procedure: Surgery
11		Recruiting		Study of Depression, Peptides, and Steroids in Cushing's Syndrome
				Condition:		Cushing's Syndrome
				Intervention:
12		Recruiting		Safety and Efficacy of Different Dose Levels of Pasireotide in Patients With de Novo, Persistent or Recurrent Cushing's Disease
				Condition:		Cushing's Disease
				Intervention:		Drug: Pasireotide
13		Completed		Hippocampal Complex Volume and Memory Dysfunction in Cushing's Syndrome
				Condition:		Cushing's Syndrome
				Intervention:
14		Active, not recruiting		A Study to Assess SOM230 in Patients With Pituitary Cushing's Disease
				Condition:		Cushing's Syndrome
				Intervention:		Drug: SOM230 s.c.
15		Completed		Cognition, Steroids, and Imaging in Cushings Disease
				Condition:		Cushing Syndrome
				Intervention:
16		Completed		Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency
				Conditions:		Adrenal Gland Hyperfunction; Adrenal Gland Hypofunction; Cushing's Syndrome; Healthy
				Intervention:		Drug: Ovine Corticotropin-Releasing Hormone (oCRH)
17		Recruiting		Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex
				Conditions:		Cushing's Syndrome; Hereditary Neoplastic Syndrome; Lentigo; Neoplasm; Testicular Neoplasm
				Intervention:
18		Recruiting		An Investigation of Pituitary Tumors and Related Hypothalmic Disorders
				Conditions:		Abnormalities; Craniopharyngioma; Cushing's Syndrome; Endocrine Disease; Pituitary Neoplasm
				Intervention:
19		Recruiting		Rosiglitazone in Treating Patients With Newly Diagnosed ACTH-Secreting Pituitary Tumor (Cushing's Disease)
				Condition:		Brain and Central Nervous System Tumors
				Interventions:		Drug: rosiglitazone maleate; Procedure: laboratory biomarker analysis
20		Recruiting		Preclinical Study Towards an Immunotherapy in Adrenocortical Carcinoma
				Conditions:		Adrenocortical Carcinoma; Cushing's Syndrome
				Intervention:
21		Completed		Heart Disease Risk Factors in Major Depression
				Conditions:		Adrenal Gland Hyperfunction; Cardiovascular Disease; Involutional Depression
				Intervention:
22		Recruiting		Adrenal Tumors - Pathogenesis and Therapy
				Conditions:		Adrenal Tumors; Adrenocortical Carcinoma; Cushing Syndrome; Conn Syndrome; Pheochromocytoma
				Intervention:
23		Recruiting		Adolescence, Puberty, and Emotion Regulation
				Conditions:		Mood Disorder; Neurobehavioral Manifestation; Healthy
				Intervention:
24		Completed		Dynamics of Leptin and Endocrine Function
				Conditions:		Healthy; Involutional Depression
				Intervention:
25		Recruiting		Study of Adrenal Gland Tumors
				Condition:		Adrenal Gland Neoplasm
				Intervention:
26		Completed		Metabolic Effects of Acute Cortisol Withdrawal in Adrenal Failure
				Condition:		Addison Syndrome
				Intervention:		Drug: hydrocortisone substitution therapy versus withdrawal
27		Recruiting		Rosiglitazone in Treating Patients With Pituitary Tumors
				Condition:		Brain and Central Nervous System Tumors
				Intervention:		Drug: rosiglitazone maleate
28		Recruiting		Examination of Brain Serotonin Receptors in Patients With Mood Disorders
				Condition:		Mood Disorder
				Intervention:
29		Completed		Pharmacist Assisted Medication Program Empowering Regulation of Diabetes
				Condition:		Diabetes Mellitus, Type 2
				Interventions:		Other: Pharmacist collaboration in diabetes care; Other: Usual care
30		Recruiting		A Study of rhuMAb IFNalpha in Adults With Systemic Lupus Erythematosus
				Condition:		Systemic Lupus Erythematosus
				Intervention:		Drug: rhuMAb IFNalpha
31		Recruiting		Etanercept for the Treatment of Lupus Nephritis
				Condition:		Lupus Nephritis
				Interventions:		Drug: Etanercept; Drug: Lupus Treatment