Thursday, July 10, 2008

Adrenal Clinical Trials

From NIH



1
Recruiting
Adrenal Scans With Radioiodine-Labeled Norcholesterol (NP-59)
Conditions:
Adrenal Tumors; Adrenal Malignancies; Abnormal Hormonal Secretions; Electrolytes Abnormalities
Intervention:
Other: Imaging, Adrenal acans

2
Not yet recruiting
Trial of Vasopressin and Epinephrine to Epinephrine Only for In-Hospital Pediatric Cardiopulmonary Resuscitation
Conditions:
Cardiopulmonary Arrest; Cardiac Arrest
Interventions:
Drug: Vasopressin; Drug: Epinephrine

3
Recruiting
Adrenal Suppression and Adrenal Recovery Induced by Megestrol Acetate
Condition:
Adrenal Function
Intervention:
Drug: megestrol acetate

4
Recruiting
Low-Dose Epinephrine Infusion Tests in Adolescent and Pediatric Patients
Condition:
Congenital Disorders
Intervention:
Drug: Epinephrine

5
Recruiting
Adrenal Function in Critical Illness
Condition:
Adrenal Insufficiency
Intervention:


6
Recruiting
Adrenal Insufficiency in Critical Emergencies in Digestive Diseases
Conditions:
Digestive Diseases; Adrenal Insufficiency; Gastrointestinal Bleeding; Variceal Bleeding; Acute Pancreatitis
Intervention:


7
Recruiting
Adrenal Function in Patients With Newly Diagnosed Lung Cancer
Conditions:
Lung Cancer; Adrenal Insufficiency
Intervention:


8
Recruiting
Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis
Conditions:
Sepsis; Adrenal Insufficiency
Intervention:
Drug: Fludrocortisone

9
Recruiting
Comparison of Two Forms of Hydrocortisone in Patients With Congenital Adrenal Hyperplasia
Conditions:
Congenital Adrenal Hyperplasia; 21-Hydroxylase Deficiency; Adrenogenital Syndrome
Intervention:
Drug: Chronocort for the treatment of CAH

10
Recruiting
Comparing Vasopressin and Adrenaline in Patients With Cardiac Arrest
Condition:
Cardiac Arrest
Interventions:
Drug: Vasopressin; Drug: Adrenaline

11
Recruiting
Adrenal Tumors - Pathogenesis and Therapy
Conditions:
Adrenal Tumors; Adrenocortical Carcinoma; Cushing Syndrome; Conn Syndrome; Pheochromocytoma
Intervention:


12
Recruiting
Adrenal Function After Living Kidney Donation
Conditions:
Addison Disease; Hypoaldosteronism
Intervention:
Procedure: Laparoscopic hand-assisted donor nephrectomy

13
Recruiting
Study of Adrenal Gland Tumors
Condition:
Adrenal Gland Neoplasm
Intervention:


14
Recruiting
Research Study for Children With Salt Wasting Congenital Adrenal Hyperplasia
Condition:
Adrenal Hyperplasia, Congenital
Intervention:
Drug: Hydrocortisone sodium acetate

15
Recruiting
Qualitative Research on Women With Congenital Adrenal Hyperplasia
Conditions:
Adrenal Hyperplasia, Congenital; Psychosexual Development; Sexual Development; Intersex; Congenital Adrenal Hyperplasia
Intervention:
Other: Interview

16
Recruiting
Dexamethasone Treatment of Congenital Adrenal Hyperplasia
Condition:
Adrenal Hyperplasia, Congenital
Intervention:
Drug: dexamethasone

17
Recruiting
Does Topical Steroid Treatment Impair the Adrenal Function?
Conditions:
Hypothalamus-Pituitary-Adrenal Axis Assessement; Topical Steroid Therapy in Chronic Skin Diseases
Intervention:


18
Recruiting
Evaluation of 123I-Iodometomidate for Adrenal Scintigraphy
Conditions:
Adrenal Tumor; Adrenocortical Carcinoma
Intervention:
Drug: 123I-Iodometomidate

19
Not yet recruiting
Safety of Epidural Fentanyl and Adrenalin During Childbirth
Conditions:
Pregnancy; Pain
Interventions:
Drug: adrenalin; Drug: placebo

20
Not yet recruiting
Adrenal Insufficiency in Cirrhotics With Ascites. Effects of Hydrocortisone on Renal and Haemodynamic Function
Condition:
Cirrhosis With Ascites
Interventions:
Drug: hydrocortisone; Drug: dextrose solution 5%

21
Not yet recruiting
Hypoglycemia Associated Autonomic Failure in Type 1 DM, Q4
Condition:
Type 1 Diabetes
Interventions:
Drug: epinephrine; Drug: epinephrine

22
Recruiting
Gene Polymorphisms Influencing Steroid Synthesis and Action
Conditions:
Disorders of Sex Development; Congenital Adrenal Hyperplasia; Congenital Adrenal Hypoplasia; Adrenal Insufficiency; Mineralocorticoid Deficiency
Intervention:
Procedure: blood drawing

23
Recruiting
Role of the Protein Osteoprotegerin in the Bone Health of Women With Congenital Adrenal Hyperplasia
Condition:
Adrenal Hyperplasia, Congenital
Intervention:


24
Recruiting
Antineoplaston Therapy in Treating Patients With Stage IV Adrenal Gland Cancer
Condition:
Adrenocortical Carcinoma
Interventions:
Drug: antineoplaston A10; Drug: antineoplaston AS2-1

25
Recruiting
Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion
Condition:
Cushing's Syndrome
Intervention:
Drug: Mifepristone

26
Not yet recruiting
Hypoglycemia Associated Autonomic Failure in Type 1 DM, Q5
Condition:
Type 1 Diabetes
Interventions:
Drug: epinephrine; Drug: epinephrine

27
Recruiting
Determining the Long-Term Effects of Prenatal Dexamethasone Treatment in Children With 21-Hydroxylase Deficiency and Their Mothers
Condition:
Adrenal Hyperplasia, Congenital
Intervention:


28
Recruiting
Natural History Study of Patients With Excess Androgen
Conditions:
Excess Androgen; Congenital Adrenal Hyperplasia (CAH); Familial Male-Limited Precocious Puberty (FMPP)
Intervention:


29
Recruiting
A Phase I Study in Asthma Patients Evaluating the Effect of Doses of FlutiForm™ on the Amount, if Any, of Cortisol Produced by the Adrenal Glands
Condition:
Asthma
Interventions:
Drug: FlutiForm 250/10 ug; Drug: FlutiForm 100/10 ug; Drug: Oral Prednisone 10mg; Drug: Placebo

30
Recruiting
Does Inhaled Busedonide or Fluticasone Impair Adrenal Function?
Condition:
Adrenal Insufficency
Intervention:


31
Recruiting
Does Intravitreal Injection of Triamcinolone Acetonide Impairs the Adrenal Function
Condition:
Secondary Adrenal Insuffisency
Intervention:


32
Recruiting
ACTH Stimulation and G Protein
Condition:
Adrenal Sufficiency
Intervention:


33
Recruiting
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Children
Conditions:
Autoimmune Disease; Congenital Adrenal Hyperplasia; Healthy; Mental Disorder Diagnosed in Childhood; Neurologic Manifestations
Intervention:


34
Recruiting
D2 Dopamine Receptor on Human Aldosterone-Producing Adenoma and Its Role in Aldosterone Secretion and Cell Proliferation
Conditions:
Hypertension; Adrenal Aldosterone-Producing Adenoma
Intervention:


35
Recruiting
Adrenal Function and Use of Intralesional Triamcinolone Acetonide 10 mg/mL in Patients With Alopecia Areata
Condition:
Alopecia Areata
Intervention:
Drug: Triamcinolone Acetonide 10 mg/mL

36
Recruiting
Adrenal and Gonadal Hormone Replacement in Anorexia Nervosa
Condition:
Anorexia Nervosa
Intervention:
Drug: DHEA + Hormone replacement therapy (estrogen/progestin)

37
Recruiting
Natural History Study of Infants With Adrenal Masses Found on Prenatal and/or Neonatal Imaging
Conditions:
Adrenocortical Carcinoma; Neuroblastoma; Precancerous/Nonmalignant Condition
Interventions:
Procedure: computed tomography; Procedure: magnetic resonance imaging

38
Recruiting
Regional Anesthesia Block of the Transversus Abdominis Plane in Children Undergoing Gastric Tube Insertion
Conditions:
Anesthesia; Enteral Nutrition
Interventions:
Procedure: bupivacaine with epinephrine (mid and upper abdomen); Procedure: bupivacaine with epinephrine (transversus abdominis plane)

39
Recruiting
Hemodynamics and Extravascular Lung Water in Acute Lung Injury
Condition:
Acute Lung Injury
Interventions:
Drug: Diuresis (furosemide) part I; Other: Fluid Bolus (crystalloid or albumin); Other: Fluid Bolus (crystalloid or albumin); Drug: Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine); Drug: Vasopressors (Norepinephrine, Vasopressin, Phenylephrine, Epinephrine); Drug: Dobutamine; Drug: Dobutamine; Other: Concentrate all drips and nutrition; Drug: Diuresis (furosemide) part II; Procedure: Dialysis

40
Recruiting
Effect of Calcipotriol Plus Hydrocortisone Ointment on the Adrenal Hormone Balance and Calcium Metabolism in Patients With Psoriasis Vulgaris on the Face and Skin Folds
Condition:
Psoriasis Vulgaris
Intervention:
Drug: Calcipotriol plus hydrocortisone (LEO 80190)

41
Recruiting
Hypothalamus-Pituitary-Adrenal Axis and Use of Mifepristone for Psychotic Depression
Condition:
Depression
Interventions:
Drug: Mifepristone; Drug: Placebo

42
Recruiting
Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex
Conditions:
Cushing's Syndrome; Hereditary Neoplastic Syndrome; Lentigo; Neoplasm; Testicular Neoplasm
Intervention:


43
Recruiting
Examining Genetic Differences Among People With 21-Hydroxylase Deficiency
Condition:
21-Hydroxylase Deficiency
Intervention:
Procedure: Hydrocortisone withdrawal

44
Recruiting
Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty
Condition:
Osteoarthritis of the Knee
Interventions:
Drug: ropivacaine; Drug: adrenaline; Drug: ketorolac; Drug: morphine; Drug: fentanyl; Drug: bupivacaine

45
Recruiting
Post Operative Hemodynamic Function After Anesthetic Induction With Etomidate for Cardiac Surgery With ECC
Condition:
Cardiac Surgery
Interventions:
Drug: etomidate; Drug: propofol

46
Recruiting
Endocrine and Psychological Evaluation of Adopted Children
Condition:
Psychosocial Adjustment
Intervention:


47
Recruiting
The Effects of Case Management in a Medicaid Managed Care Plan
Conditions:
Neoplasms; Heart Diseases; Adrenal Cortex Diseases
Intervention:
Behavioral: Case management

48
Recruiting
Mutation Analysis of 17α-Hydroxylase
Conditions:
Pseudohermaphroditism; Congenital Adrenal Hyperplasia; Hypertension
Intervention:
Procedure: blood drawing

49
Recruiting
Cesarean Delivery and Post-Operative Pain Management With Local Anesthesia
Condition:
Pain, Postoperative
Intervention:
Drug: .5% bupivacaine with epinephrine

50
Recruiting
A Study of the Efficacy and Safety of CORLUX in the Treatment of Endogenous Cushing's Syndrome
Condition:
Cushing's Syndrome
Intervention:
Drug: mifepristone