Friday, April 26, 2013

Ectopic Cushing's Syndrome Secondary to Pulmonary Carcinoid Tumor


Shahriar Hashemzadeh, MD, Atabak Asvadi Kermani, MD, Akbar Ali-Asgharzadeh, MD, Moneireh Halimi, MD, Mina Soleimani, MD, Amirhosein Ladan, MD

The Annals of Thoracic Surgery, Volume 95, Issue 5, May 2013, Pages 1797-1799 

http://dx.doi.org/10.1016/j.athoracsur.2012.09.039

Adrenocorticotropic hormone (ACTH) overproduction within the pituitary gland or ectopically leads to hypercortisolism.

In this study a case of Cushing's syndrome caused by an ectopic ACTH-secreting carcinoid tumor in lung is discussed, as are the available diagnostic procedures.

The patient was a 28-year-old woman with clinical features starting about 6 months previously. The results of her biochemical tests suggested ectopic Cushing's syndrome.

Full-body computed tomography revealed a single nodule in the inferior lobe of the right lung.

After removal of the nodule, the patient's symptoms subsided clinically, and laboratory tests confirmed remission of the hypercortisolism.

View Full Text