Tuesday, May 3, 2011

NIH Cushing's Clinical Trials Updated 5/3/2011

Rank Status Study
1 Recruiting Preoperative Bexarotene Treatment for Cushing's Disease
Condition: Cushing's Disease
Intervention: Drug: Bexarotene
2 Recruiting Safety and Efficacy of LCI699 in Cushing's Disease Patients
Condition: Cushing Disease
Intervention: Drug: LCI699
3 Recruiting Rosiglitazone in Treating Patients With Newly Diagnosed ACTH-Secreting Pituitary Tumor (Cushing Disease)
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: rosiglitazone maleate;   Other: laboratory biomarker analysis
4 Recruiting An Investigation of Pituitary Tumors and Related Hypothalmic Disorders
Conditions: Abnormalities;   Craniopharyngioma;   Cushing's Syndrome;   Endocrine Disease;   Pituitary Neoplasm
Intervention:
5 Recruiting Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex
Conditions: Cushing's Syndrome;   Hereditary Neoplastic Syndrome;   Lentigo;   Neoplasm;   Testicular Neoplasm
Intervention:
6 Unknown  Study of Depression, Peptides, and Steroids in Cushing's Syndrome
Condition: Cushing's Syndrome
Intervention:
7 Recruiting Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion
Condition: Cushing's Syndrome
Intervention: Drug: Mifepristone
8 Recruiting Insulin Sensitivity and Substrate Metabolism in Patients With Cushing's Syndrome
Conditions: Cushing's Syndrome;   Insulin Resistance
Intervention: Procedure: Surgery
9 Recruiting New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome
Condition: Cushing Syndrome
Intervention:
10 Unknown  Glucocorticoid Receptor Antagonism in Subclinical Cushings
Condition: Sub-Clinical Cushing's Syndrome
Intervention: Drug: Mifepristone
11 Not yet recruiting Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome
Condition: Adrenal Tumour With Mild Hypercortisolism
Intervention: Procedure: Adrenalectomy
12 Recruiting Adrenal Tumors - Pathogenesis and Therapy
Conditions: Adrenal Tumors;   Adrenocortical Carcinoma;   Cushing Syndrome;   Conn Syndrome;   Pheochromocytoma
Intervention:
13 Recruiting Adolescence, Puberty, and Emotion Regulation
Conditions: Mood Disorder;   Neurobehavioral Manifestation;   Healthy
Intervention:
14 Recruiting Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin
Conditions: Pancreatic Neoplasm;   Pituitary Neoplasm;   Nelson Syndrome;   Ectopic ACTH Syndrome
Intervention: Drug: Pasireotide LAR
15 Recruiting Study of Adrenal Gland Tumors
Condition: Adrenal Gland Neoplasm
Intervention:
16 Recruiting Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma
Condition: Pituitary Tumor
Intervention:

 

Indicates status has not been verified in more than two years