NIH Cushing's Clinical Trials Updated 5/3/2011

Rank	Status	Study
1	Recruiting	Preoperative Bexarotene Treatment for Cushing's Disease Condition: Cushing's Disease Intervention: Drug: Bexarotene
2	Recruiting	Safety and Efficacy of LCI699 in Cushing's Disease Patients Condition: Cushing Disease Intervention: Drug: LCI699
3	Recruiting	Rosiglitazone in Treating Patients With Newly Diagnosed ACTH-Secreting Pituitary Tumor (Cushing Disease) Condition: Brain and Central Nervous System Tumors Interventions: Drug: rosiglitazone maleate;   Other: laboratory biomarker analysis
4	Recruiting	An Investigation of Pituitary Tumors and Related Hypothalmic Disorders Conditions: Abnormalities;   Craniopharyngioma;   Cushing's Syndrome;   Endocrine Disease;   Pituitary Neoplasm Intervention:
5	Recruiting	Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex Conditions: Cushing's Syndrome;   Hereditary Neoplastic Syndrome;   Lentigo;   Neoplasm;   Testicular Neoplasm Intervention:
6	Unknown †	Study of Depression, Peptides, and Steroids in Cushing's Syndrome Condition: Cushing's Syndrome Intervention:
7	Recruiting	Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion Condition: Cushing's Syndrome Intervention: Drug: Mifepristone
8	Recruiting	Insulin Sensitivity and Substrate Metabolism in Patients With Cushing's Syndrome Conditions: Cushing's Syndrome;   Insulin Resistance Intervention: Procedure: Surgery
9	Recruiting	New Imaging Techniques in the Evaluation of Patients With Ectopic Cushing Syndrome Condition: Cushing Syndrome Intervention:
10	Unknown †	Glucocorticoid Receptor Antagonism in Subclinical Cushings Condition: Sub-Clinical Cushing's Syndrome Intervention: Drug: Mifepristone
11	Not yet recruiting	Adrenalectomy Versus Follow-up in Patients With Subclinical Cushings Syndrome Condition: Adrenal Tumour With Mild Hypercortisolism Intervention: Procedure: Adrenalectomy
12	Recruiting	Adrenal Tumors - Pathogenesis and Therapy Conditions: Adrenal Tumors;   Adrenocortical Carcinoma;   Cushing Syndrome;   Conn Syndrome;   Pheochromocytoma Intervention:
13	Recruiting	Adolescence, Puberty, and Emotion Regulation Conditions: Mood Disorder;   Neurobehavioral Manifestation;   Healthy Intervention:
14	Recruiting	Study of Pasireotide in Patients With Rare Tumors of Neuroendocrine Origin Conditions: Pancreatic Neoplasm;   Pituitary Neoplasm;   Nelson Syndrome;   Ectopic ACTH Syndrome Intervention: Drug: Pasireotide LAR
15	Recruiting	Study of Adrenal Gland Tumors Condition: Adrenal Gland Neoplasm Intervention:
16	Recruiting	Prevalence of Pituitary Incidentaloma in Relatives of Patients With Pituitary Adenoma Condition: Pituitary Tumor Intervention:

 

† Indicates status has not been verified in more than two years