Showing posts with label episodic. Show all posts
Showing posts with label episodic. Show all posts

Thursday, December 10, 2009

(Ectopic) Cushing's syndrome associated with an islet-cell tumour of the pancreas in a boy aged 2 years.

J. H. Burkinshaw, D. O'Brien, and J. E. Pendower

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (2.8M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

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Images in this article

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  • ALLOTT EN, SKELTON MO. Increased adrenocortical activity associated with malignant disease. Lancet. 1960 Aug 6;2(7145):278–284. [PubMed]
  • BAGSHAWE KD. Hypokalaemia, carcinoma and Cushing's syndrome. Lancet. 1960 Aug 6;2(7145):284–287. [PubMed]
  • BALLS KF, NICHOLSON JT, GOODMAN HL, TOUCHSTONE JC. Functioning islet-cell carcinoma of the pancreas with Cushing's syndrome. J Clin Endocrinol Metab. 1959 Sep;19:1134–1143. [PubMed]
  • PIERRE-BOURGEOIS, ROGE J, CLEMENT D, MARTIN E, DESCAMPS J. [Hypercorticism syndrome and pancreatic cancer of the Langerhans type.]. Bull Mem Soc Med Hop Paris. 1959 Jun 19;75:665–671. [PubMed]
  • DEL CASTILLO EB, TRUCCO E, MANZUOLI J. Maladie de Cushing et cancer du pancréas. Presse Med. 1950 Jul 5;58(43):783–785. [PubMed]
  • CHRISTY NP. Adrenocorticotrophic activity in the plasma of patients with Cushing's syndrome associated with pulmonary neoplasms. Lancet. 1961 Jan 14;1(7168):85–86. [PubMed]
  • Friedman M, Marshall-Jones P, Ross EJ. Cushing's syndrome: adrenocortical hyperactivity secondary to neoplasms arising outside the pituitary-adrenal system. Q J Med. 1966 Apr;35(138):193–214. [PubMed]
  • JARETT L, LACY PE, KIPNIS DM. CHARACTERIZATION BY IMMUNOFLUORESCENCE OF AN ACTH-LIKE SUBSTANCE IN NONPITUITARY TUMORS FROM PATIENTS WITH HYPERADRENOCORTICISM. J Clin Endocrinol Metab. 1964 Jun;24:543–549. [PubMed]
  • MARKS V, SAMOLS E, BOLTON R. HYPERINSULINISM AND CUSHING'S SYNDROME. Br Med J. 1965 May 29;1(5447):1419–1420. [PubMed]
  • MEADOR CK, LIDDLE GW, ISLAND DP, NICHOLSON WE, LUCAS CP, NUCKTON JG, LUETSCHER JA. Cause of Cushing's syndrome in patients with tumors arising from "nonendocrine" tissue. J Clin Endocrinol Metab. 1962 Jul;22:693–703. [PubMed]
  • NICHOLS J, GOURLEY W. Adrenal weight-maintaining corticotropin in carcinoma of lung. JAMA. 1963 Aug 31;185:696–698. [PubMed]
  • O'Riordan JL, Blanshard GP, Moxham A, Nabarro JD. Corticotrophin-secreting carcinomas. Q J Med. 1966 Apr;35(138):137–147. [PubMed]
  • ROSENBERG AA. Fulminating adrenocortical hyperfunction associated with islet-cell carcinoma of the pancreas; case report. J Clin Endocrinol Metab. 1956 Oct;16(10):1364–1373. [PubMed]
  • Ross EJ, Marshall-Jones P, Friedman M. Cushing's syndrome: diagnostic criteria. Q J Med. 1966 Apr;35(138):149–192. [PubMed]

Articles from Archives of Disease in Childhood are provided here courtesy of

BMJ Group

From http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2019792/

Saturday, July 12, 2008

Coming Thursday, July 17

An interview with Kate (Fairley).

Kate Kate (Fairley) has had symptoms since 1991. She has had two pituitary surgeries and another recurrence. She is not yet cured and her current diagnoses are Idiopathic Intracranial Hypertension, panhypopituiarism and a CSF leak. Kate writes in her message board signature:

  • 1991 - Symptoms began
  • Oct. 4, 2006 - Testing begins with Dr. F
  • Dec. 24, 2006 - Dx of Episodic Cushing's Disease
  • Jan. 5, 2007 - 1st pit surgery with Dr. J in P'burgh
  • April 3, 2007 - Confirmation of path-proven ACTH-secreting adenoma
  • June 18-22, 2007 - Testing with Dr. L for recurrence at Swedish in Seattle
  • July 13, 2007 - Dx of Recurrence of Episodic Cushing's Disease
  • July 26, 2007 - Dr. McC @ MD Anderson confirms existence of recurrent tumor on right side
  • July 27, 2007 - 2nd pit surgery with Dr. J in P'burgh; removal of tumor from right side of pit
  • Oct. 10, 2007 - CSF leak repair surgery
  • March 2008 - recurrence suspected but cannot test due to cortisol-lowering narcotics for suspected osteonecrosis of left hip.
  • Idiopathic Intracranial Hypertension, panhypopituiarism, CSF leak, and, for now....
  • No cure for me. :(

Pituitary Cushings: Kate and Dr. Ted Friedman on National Geographic TV were featured on the National Geographic channel. The show, called the Science of Obesity, has a segment on Cushing's syndrome.

Today, 127 million adult Americans are considered overweight, but few reach the extreme proportions of the exceptionally obese. What are the physical stresses of weighing more than 500 pounds and what steps can reverse it? NGC provides an understanding of what happens inside the bodies of these massive people & why a person can pack on hundreds more pounds than those with typical weight challenges. The show explores the genetics behind weight gain & medical advances available to help prevent it.

I hope that all of you can watch this. Please consider contacting your local media about doing your story! There is still much work to do to increase Cushing's awareness.

Discuss this TV show.

More about Dr Ted Friedman

Read Kate's articles:

Attend Kate's Interview on July 17, 2008, 7:30PM Eastern