Thursday, November 18, 2010

What causes Cushing’s syndrome and Cushing’s disease?

Cushing’s syndrome can be caused by medication or by a tumor. Sometimes, there is a tumor of the adrenal gland that makes too much cortisol. It may also be caused by a tumor in the pituitary gland (a small gland under the brain that produces hormones that in turn regulate the body’s other hormone glands).

Some pituitary tumors produce a hormone called adrenocorticotropic hormone (ACTH ), which stimulates the adrenal glands and causes them to make too much cortisol. This is termed Cushing’s disease. ACTH -producing tumors can also originate elsewhere in the body and these are referred to as ectopic tumors.

It is important to note that pituitary tumors are almost never cancerous.

 

From http://www.medicaltoday.net/what-causes-cushing%E2%80%99s-syndrome-and-cushing%E2%80%99s-disease.html